Latest Research on IGF-1 Analog (Long R3)
Introduction
IGF-1 Analog (Long R3) represents a significant area of active research in peptide science. This comprehensive guide explores the latest developments, mechanisms of action, and research applications of IGF-1 Analog (Long R3) in laboratory settings.
Understanding IGF-1 Analog (Long R3)
IGF-1 LR3 is an 83-amino-acid polypeptide comprising native IGF-1 with an Arg3 substitution and an additional 13-residue N-terminal extension (MFPAMPLLSGLRS) that attenuates IGF binding protein association and extends half-life in experimental systems. Investigators leverage the analog to study PI3K/Akt and MAPK signaling cascades, myocyte differentiation, and receptor trafficking in cell culture. Reconstitute the lyophilized material in acidic buffer (pH 4.0-5.0) with carrier protein if required, then aliquot and store at -20 C. Supplied strictly for in vitro and ex vivo research. Not for human or veterinary use.
Chemical Properties
Research Applications
Cell Culture Research
Researchers employ IGF-1 Analog (Long R3) to investigate cell culture research in controlled laboratory environments.
Protein Biochemistry
Researchers employ IGF-1 Analog (Long R3) to investigate protein biochemistry in controlled laboratory environments.
Molecular Signaling
Researchers employ IGF-1 Analog (Long R3) to investigate molecular signaling in controlled laboratory environments.
Mechanisms of Action
Current research focuses on understanding the precise mechanisms through which IGF-1 Analog (Long R3) interacts at the cellular and molecular levels. Studies investigate receptor binding, signal transduction pathways, and downstream cellular responses.
Quality Considerations for Research
For research applications, ensuring peptide purity and stability is paramount:
Recent Research Developments
1. Intranasal long R3 insulin-like growth factor-1 treatment promotes ...
Nov 29, 2024 ... Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive ...
**Source:** pubmed.ncbi.nlm.nih.gov
2. Intranasal long R3 insulin-like growth factor-1 treatment promotes ...
Long arginine 3-IGF-1 (LR3-IGF-1) is a potent IGF-1 analogue. We sought to ... In vitro, uptake of Aβ1–42 peptide by BV2 cells was enhanced by LR3-IGF ...
**Source:** journals.sagepub.com
3. Tirzepatides | High-Purity Peptides for ResearchIGF-LR3
IGF-LR3 (Insulin-Like Growth Factor Long R3) is a synthetic, stabilized analogue of human IGF-1 designed specifically for laboratory research. With a ...
**Source:** purapeptides.com
Related Research Products
Researchers may also be interested in related compounds:
Research Methodology
Proper research protocols emphasize controlled experimental conditions and reproducible methodology. Researchers should adhere to institutional guidelines and ethical standards.
Future Directions
Emerging research continues to explore new applications and mechanisms of action for IGF-1 Analog (Long R3). As our understanding deepens, these compounds may provide valuable tools for advancing scientific knowledge.
Conclusion
IGF-1 Analog (Long R3) represents an important area of active research with significant potential for advancing our understanding of biological processes. Continued investigation in controlled laboratory settings will further illuminate the mechanisms and applications of these compounds.
Research Disclaimer
All products discussed are for laboratory research use only. They have not been approved for human or animal use by any regulatory agency. Researchers must comply with all applicable laws, regulations, and institutional guidelines.
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Research-Grade IGF-1 Analog (Long R3) Available
For researchers seeking high-purity IGF-1 Analog (Long R3) for laboratory studies, Purgo Labs offers premium research-grade peptides with verified purity certificates and comprehensive analytical data. Our products undergo rigorous quality control to ensure consistency and reliability for your research applications.